Programme
THURSDAY 16TH SEPTEMBER 2021
Session 1 – Opening – 10th IMPC Anniversary
(Chair: Radislav Sedláček)
10:00 – 10:20
Radislav Sedláček, Institute of Molecular Genetics, Czech Academy of Sciences, Czech Republic – Welcoming lecture
Keynote lecture
10:20 – 11:00
Steve Brown, MRC Harwell Institute, United Kingdom – “Illuminating the dark genome: genome-wide approaches for understanding the genetic basis of disease”
Session 2 – Immunology and infections
(Chair: Radislav Sedláček)
11:00 – 11:20
Daniel Růžek, Institute of Parasitology, Biology Centre, Czech Academy of Sciences, Czech Republic – “Neutralizing antibodies for prophylaxis and therapy of viral infections”
11:20 – 11:40
Peter Šebo, Institute of Microbiology, Czech Academy of Sciences, Czech Republic – “A new mouse model of shedding and transmission of the pertussis agent”
11:40 – 12:00
Bernard Malissen, Centre d’Immunologie de Marseille-Luminy & Center for Immunophenomics, Marseille, France – “Pre-clinical mouse models of immune disorders and immunotherapies”
12:00 – 12:30
Discussion with speakers
12:30 – 14:00
Lunch break
Session 3 – Short technology talks (commercial talks)
(Chair: Vendula Novosadová)
14:00 – 14:10
Milan Kopecek, FUJIFILM Visualsonics, Amsterdam, Netherlands – “Multimodal molecular imaging in (pre) clinical research”
14:10 – 14:20
Sable Systems
14:20 – 14:30
Pilhan Kim, Graduate School of Medical Science and Engineering, KAIST, Korea – “IntraVital Microscopy (IVM): In Vivo Live Cell Imaging Platform” – talk sponsored by Accela
14:30 – 14:40
Dilip Verma, TSE Systems, Germany – “Automated cognitive & behavioral screening of individual mice living in social groups, reducing stress component”
Poster session 1
14:40 – 15:40
Interactive poster viewing
Session 4– Disease models
(Chair: Petr Kašpárek)
15:40 – 16:00
Aich Abhishek, University Medical Center Göttingen, Germany – “Modelling human mitochondrial translation dysfunction in mice”
16:00 – 16:20
Gary Thomas, University of Pittsburgh, United States – “Dangerous liaisons: A rogue PACS1/HDAC6 interaction in PACS1 Syndrome”
16:20 – 16:40
Discussion with speakers
FRIDAY 17TH SEPTEMBER 2021
Keynote lecture
(Chair: Radislav Sedláček)
09:30 – 10:00
Jakub Abramson, Weizmann Institute of Science, Israel – “Tooth autoimmunity – from broken central tolerance to broken teeth”
Session 5 – Advances in neurosciences (A)
(Chair: Jan Rozman)
10:00 – 10:15
Jan Rozman, Institute of Molecular Genetics, Czech Academy of Sciences, Czech Republic – Opening of the session
10:15 – 10:35
Sabine Hölter-Koch, Helmholtz Zentrum Munich, Germany – “Translational issues beyond data quality”
10:35 – 10:55
Oliver Stiedl, VU University Amsterdam, Netherlands – “Integrative home cage-based phenotyping of mouse models of emotional and cognitive dysfunction”
10:55 – 11:15
Stephan von Hörsten, Friedrich-Alexander-Universität Erlangen-Nürnberg, Germany – “Characterization of alpha-synuclein transgenic mice and rats for prodromal Parkinson´s disease”
11:15 – 11:35
Discussion with speakers
11:35 – 11:50
Break
Session 5 – Advances in neurosciences (B)
(Chair: Jan Rozman)
11:50 – 12:10
Martien Kas, University of Groningen, Netherlands – “Linking neuropsychiatry to quantitative biology: a translational and transdiagnostic approach”
12:10 – 12:30
Wieland Huttner, MPI-CBG, Germany – “Neural stem cells, human-specific genes, and neocortex expansion in development and human evolution”
12:30 – 12:45
Discussion with speakers
12:45 – 14:00
Lunch break
Session 6 – Preclinical development
(Chair: Karel Chalupský)
14:00 – 14:20
Vladimír Divoký, Palacky University Olomouc, Faculty of Medicine, Czech Republic – “Validation of drug targets and testing of new compounds in mixed-lineage leukemia using xenograft and humanized knock-in mouse models”
14:20 – 14:40
Cord Brakebusch, University of Copenhagen, Biotech Research & Innovation Centre, Denmark – “Epigenetic inhibitor increasing HDR efficiency”
14:40 – 15:00
Branislav Kovacech, AXON Neuroscience, Slovakia – “The second generation of therapeutic antibodies against COVID-19”
15:00 – 15:15
Discussion with speakers
Session 7 – Short talks selected from poster presentations
(Chair: Vendula Novosadová)
15:15 – 15:25
Zuzana Koledová, Masaryk University, Faculty of Medicine, Czech Republic – “Studying breast development and lactation biology using mouse models“
15:25 – 15:35
Jan Křivánek, Masaryk University, Faculty of Medicine, Czech Republic – “Unique stem cell subpopulation ensures mesenchymal regeneration of continuously growing teeth“
15:35 – 15:45
Roldan Medina De Guia, Institute of Molecular Genetics, Czech Academy of Sciences, Czech Republic – “Defining and Establishing Clinical Blood Chemistry Reference Intervals for The International Mouse Phenotyping Consortium”
15:45 – 15:55
Goretti Aranaz Novaliches, Institute of Molecular Genetics, Czech Academy of Sciences, Czech Republic – “Cytoplasmic Polyadenylation by TENT5A is Essential for Teeth and Bone Formation“
15:55 – 16:05
Reetta Hinttala, University of Oulu, Finland – “Analysis of human brain tissue derived from DBS surgery“
16:05 – 16:20
Break
Poster session 2
16:20 – 17:00
Interactive poster viewing
Keynote lecture
(Chair: Radislav Sedláček)
17:00 – 17:40
Yann Herault, Institut de Génétique et de Biologie Moléculaire et Cellulaire, France – “Dissecting the genetics of human syndromic disorders causing cognitive dysfunction using animal models”
Closing
17:40 – 18:00
Radislav Sedláček, Institute of Molecular Genetics, Czech Academy of Sciences, Czech Republic